1. R. Coomey,
R. Stowell, A. Majewska, D. Tropea
(2020). The Role of Microglia in
Neurodevelopmental Disorders and Their Therapeutics. Current Frontiers, In press.
2.
S.
Bach, N. M. Ryan, P. Guasoni, A. Corvin, D.
Tropea (2019) Methyl-CpG2-binding
protein 2 mediates overlapping mechanisms across brain disorders.
bioRxiv 819573; doi: https://doi.org/10.1101/819573
3.
C.
Keogh,
G. Pini, I. Gemo, D. Tropea. (2019) Statistical Modelling of
Cortical Connectivity Using Non-invasive Electroencephalograms. J. Vis. Exp. (Pending
Publication), e60249, In-press.
4.
A. Sanfeliu, W. Kaufmann, M.Gill,
P. Guasoni, D.Tropea (2019). Transcriptomic
Studies in Mouse Models of Rett Syndrome: A Review. Forefront Review Neuroscience, 413, 183-205
5. A.
Sanfeliu, K. Hokamp, M. Gill, D. Tropea
(2019). Transcriptomic
analysis of Mecp2 mutant mice reveals differentially expressed genes and
altered mechanisms in both blood and brain. Front Psychiatry.
2019 Apr 29;10:278. doi: 10.3389/fpsyt.2019.00278. eCollection 2019
6. C. Keogh, G.
Pini, A. H. Dyer, S. Bigoni, P. DiMarco, I. Gemo,, R. Reilly,
D. Tropea (2018) Clinical and Genetic Rett Syndrome Variants are Defined by Stable
Electrophysiological Profiles. BMC Pediatrics, 18(1):333. doi:
10.1186/s12887-018-1304-7
7. S.
Shovlin and D. Tropea (2018). Transcriptome
level analysis in Rett syndrome using human samples from different tissues.
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8.
D.
Tropea, N. Hardingham, K. Millar, K. Fox (2018). Mechanisms underlying
the role of DISC1 in synaptic plasticity. Invited Review. Journal of Physiology, 596(14): 2747-2771.
9.
D.Tropea,
A. Harkin (2017) Biology of brain disorders, editorial. Frontiers in Cellular
Neurosciences. 11:366. doi: 10.3389/fncel.2017.00366
10.
A. Ajetunmobi, D, McAllister, Y.
Volkov, D.Tropea and A. Prina-Mello.
"Characterisation of SH-SY5Y Human
Neuroblastoma cell growth over glass and SU-8 substrates." J Biomed Mater Res A. 2017 Mar 28. doi: 10.1002/jbm.a.36071
11.
S. Wrigley, D. Arafa, D. Tropea (2017). Insulin-Like Growth Factor 1: at the crossroad of neurodevelopment and
ageing. Frontiers in Cellular Neuroscience, 11:14. doi: 10.3389/fncel.2017.00014. eCollection
2017.
12.
C.Vadathpour, A.H. Dyer, D.Tropea (2016). Insulin-Like Growth Factor 1
and Related Compounds in the Treatment of Childhood-Onset Neurodevelopmental
Disorders. Frontiers in
Psychiatry, 10:450.
eCollection 2016.
13.
G. Pini G, S. Bigoni, L.
Congiu, A.M.Romanelli, M.F. Scusa, P. Di Marco, A. Benincasa, P. Morescalchi, A.
Ferlini, F. Bianchi, D. Tropea, M. Zappella
(2016). Rett Syndrome: a wide clinical and autonomic picture. Orphanet J Rare Dis. 2016 Sep 29;11(1):132.
14. D. Tropea, I. Molinos, S. Bellini,
M. Gill, A. Corvin (2016). Expression
of nuclear Methyl-CpG binding protein 2 (MECP2) is dependent on neuronal
stimulation and application of Insulin-like growth factor 1. Neuroscience Letters, 621:111-116.
15.
A.H. Dyer, C.Vadathpuour, A.
Sanfeliu, D.Tropea (2016). The role
of Insulin-like Growth Factor 1 (IGF1) in brain development, maturation and
neuroplasticity. Neuroscience, 325:89-99.
16.
G. Pini, L.
Congiu, A. Benincasa, P. Di Marco, S. Bigoni, A. Dyer, N. Mortimer, A. Della
Chiesa, S. O'Leary, R. McNamara, K. J. Mitchell, M. Gill and D. Tropea (2016). Illness Severity, Social &
Cognitive Ability and EEG Analysis of Ten Patients with Rett Syndrome Treated with Mecasermin (recombinant
human IGF-1): A Clinical Study. Autism Research and
Treatment. http://dx.doi.org/10.1155/2016/5073078
17. D.Tropea, I. Molinos, S.
Bellini, E. Petit, C. O’Toutaigh, I. Nagakura, K. Mitchell, M. Sur, M. Gill, J.
Waddington, A. Corvin (2016). Disrupted in schizophrenia 1 (DISC1)
mutants have impaired activity-dependent plasticity in vitro and in vivo.
Translational Psychiatry, Jan
12;6:e712. doi: 10.1038/tp.2015.206
18. Ajetunmobi, A. Prina-Mello, Y.Volkov, A. Corvin, D. Tropea (2014). The era of
nanotechnology in the brain: novel approaches to the study of the Central
Nervous System. Progress in Neurobiology. 123:
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19. D.Tropea, S. Wrigley and G.Pini
(2014). Treating Rett Syndrome: current approaches and New Therapies . Book
Chapter Rett Syndrome and Other Communication Disorders, ebook, NOVA Science publisher
Inc. 2015 New York.
20.
Nagakura, A. Van Wart, J.
Petravitz, D. Tropea, M. Sur (2014).
STAT1 regulates the homeostatic component of visual cortical plasticity via an
AMPA receptor-mediated mechanism. J. Neurosci Jul 30; 34(31):10256-63.
21.
J. Castro, S. Kwok, R.
Garcia, A. Banerjee, D. Tropea, M.
Sur (2014). Functional
recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome.
PNAS Jul 8;111(27):9941-6.
22. G. Pini, M. F. Scusa, A. Benincasa, I. Bottiglioni, L.Congiu, C.
Vadhatpour, A. M. Romanelli, I. Gemo, C. Puccetti, R.Mc Namara, S. O’Leary, A.
Corvin, M. Gill, D. Tropea (2014). Repeated IGF1 treatment in a patient with Rett
Syndrome: a single case study. Frontiers in Pediatrics. Jun 3;2:52.
doi: 10.3389/fped.2014.00052. eCollection 2014
23. Ajetunmobi
and D. Tropea. (2014) Progress
toward therapies and interventions. Invited book chapter for “The Genetics of
Neurodevelopmental Disorders”-Wiley-2015- COS Printer Pte Ltd- Singapore ,
319-344.
24. D.W. Morris,
R, Pearson, P. Cormican, e. Kenny, C. O’Dushlaine, LP Lemieux Perreault, e.
Gionnoulatou, D. Tropea, et al.
(2014). An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis. Hum. Mol. Gen., Jun
15;23(12):3316-26. doi: 10.1093/hmg/ddu025. Epub 2014 Jan 28.
25. T.
O'Donoghue, D.W. Morris, C. Fahey, A. Da Costa, S. Moore, E. Cummings, G.
Leicht, S. Karch, D. Hoerold, D. Tropea, J.J. Foxe, M. Gill, A. Corvin,
G. Donohoe (2014). Effects of ZNF804A on auditory P300 response in
schizophrenia. Transl Psychiatry. 2014 Jan 14;4:e345.
doi: 10.1038/tp.2013.115.
26. E. J. Rose,
A. Hargreaves, D. Morris, C. Fahey, D. Tropea, E. Cummings, C.
Caltagirone, P. Bossù, C. Chiapponi, F. Piras, G. Spalletta, M. Gill, A.
Corvin, G. Donohoe (2013). Effects of a novel schizophrenia risk variant
rs7914558 at CNNM2 on brain
structure and attributional style. Br J
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27.
E.M. Kenny, P. Cormican, S. Furlong, E. Heron,
G. Kenny, C. Fahey, E. Kelleher, S. Ennis, D.
Tropea, R. Anney, A. P. Corvin, G. Donohoe, L. Gallagher, M. Gill, D. W.
Morris, (2013). Excess of rare novel loss-of-function variants in synaptic
genes in schizophrenia and autism spectrum disorders. Molecular Psychiatry, Oct 15, doi: 10.1038/mp.2013.127.
28.
G. Donohoe, J. Walters, A. Hargreaves, E.J.
Rose, D.W. Morris, C. Fahey, S. Bellini, E. Cummins, I. Giegling, A.M.
Hartmann, H.J. Moller, P. Muglia, M.J. Owen, M. Gill, M.C. O’Donovan, D. Tropea, D. Rujescu, A. Corvin
(2013). Neuropsychological Effects of the CSMD1 Genome-Wide Associated
Schizophrenia Risk Variant rs10503253. Genes Brain Behav. 12(2):203-209. Jan 15
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29. D. Tropea. New challenges and
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30.
Irish Schizophrenia Genomics Consortium and the
Wellcome Trust Case Control Consortium Genome-wide association study
implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex
locus in schizophrenia. Biol.
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31.
E. J. Rose, D.W. Morris, C. Fahey, I.H.
Robertson, C. Greene, J. O’Doherty, F.N. Newell, H. Garavan, J. Mc Grath, A.
Bodke, D. Tropea, M. Gill, AP
Corvin, G. Donohoe. The effect of the neurogranin schizophrenia risk variant
rs12807809 on brain structure and function.
Twin Res. Hum. Genet. 15(3), 296-303.
32.
Corvin, I. Molinos, G. Little G. Donohue, M.
Gill, D. Morris, D. Tropea (2012).
IGF1 and its active peptide (1-3)IGF1 enhance the expression of synaptic
markers in neuronal circuits through different cellular mechanisms.
Neuroscience Letters, 520(1), 296-303.
33.
G. Pini, M.F. Scusa, B.
Felloni, L. Congiu, A. Benincasa, R. Frati, I. Bottiglioni, P. Di Marco, P.
Borelli, U. Bonuccelli, A. Della-Chiesa, A. Prina-Mello, D. Tropea (2012). Safety
assessment of IGF-1 treatment: study on six Rett patients. Autism
research and treatment, 2012:679801, Epub
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34.
Hargreaves, D.W. Morris, E. Rose, C. Fahey, S.
Moore, E. Cummings, D. Tropea, M. Gill, A. Corvin, G. Donohoe (2012). ZNF804A and social cognition in patients with schizophrenia and healthy
controls. Mol Psychiatry., Feb;17(2), 118-119.
35.
Delaney, J. McGrane, E. Cummings, DW Morris, D. Tropea, M. Gill, A. Corvin, G.
Donohoe. Preserved Cognitive function is associated with suicidal ideation and
single suicide attempts in schizophrenia. Schizophr. Res. 140 (1-3), 232-236.
36.
T. O’Donohoe, D.W. Morris, C. Fahey, A. Da
Costa, J.J. Foxe, D. Hoerold, D. Tropea,
m. Gill, A. Corvin, G. Donohoe (2012). A NOS1 variant implicated in cognitive
performance influences evoked neural responses during a high density EEG study
of early visual perception. Hum. Brain Mapp, 33(5), 1202-1211.
37. N. Mellios, H. Sugihara, J. Castro, A. Banerjee, C. Le, A. Kumar, B.
Crawford, J. Strathmann, D. Tropea, S. S. Levine, D. Edbauer, M. Sur (2011). miR-132, an
experience-dependent microRNA, is essential for visual cortex plasticity.
Nature Neurosci.,40, 1240-1242.
38. D.
Tropea, M. Sur,A. Majewska (2010) Experience-dependent
plasticity in visual cortex: dendritic spines and visual responsiveness.
Communicative and Integrative Biology 4(2), 216-219.
39. D. Tropea, A.
Majewska, R. Garcia, M. Sur (2010) Structural dynamics of synapses in vivo
correlate with functional changes during experience-dependent plasticity in
visual cortex. Journal of Neurosci. 30(33), 11086-11095.
40. C.L. McCurry,
J.D. Shepherd, D. Tropea, KH
Wang, M.F. Bear, M. Sur (2010) Loss of Arc renders the visual cortex impervious
to the effects of sensory experience or deprivation. Nat. Neurosci. Apr;13(4), 450-457
41.
D. Tropea, E. Giacometti, N. Wilson, Caroline Beard,
Cortina McCurry, Dong Dong Fu, Ruth Flannery, R. Jaenisch and M. Sur (2009)
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice. PNAS,
106 (6), 2029-2034.
42.
M. Caleo, D.
Tropea, C. Rossi, L. Gianfranceschi and L. Maffei (2009) Environmental
enrichment promotes fiber sprouting after deafferentation of the superior
colliculus in the adult rat brain. Exp. Neurol., Apr 216 (2), 515-519.
43.
D. Tropea, A. Van
Wart and M Sur (2008). Review. Molecular mechanisms of experience-dependent
plasticity in visual cortex. Philos
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44.
Lyckman, S. Horng, C. Leamey, D. Tropea, A. Watakabe, A. Van Wart, C.
McCurry, T. Yamamori and M. Sur (2008). Transcriptional regulation during the
critical period of ocular dominance plasticity: prominent expression of
actin-binding and myelination factors. PNAS,
105 (27), 9409-9414.
45. D. Tropea, G. Kreiman, A.
Lyckman, S. Mukherjee, H. Yu, S. Horng and M. Sur (2006). Gene expression
changes and molecular pathways mediating activity-dependent plasticity in
visual cortex. Nature Neuroscience, 9(5), 660-668.
46. P.P Pattabiraman, D. Tropea, C.
Chiaruttini, E. Tongiorgi, A. Cattaneo and L. Domenici (2005). Neuronal
activity regulates the developmental expression and subcellular localization of
cortical BDNF mRNA isoforms in vivo. Mol. Cell. Neurosci. 28(3),
556-570.
47.
D. Tropea, M. Caleo and L. Maffei, (2003). Synergistic
effects of brain-derived neurotrophic factor and chondroitinase ABC on retinal
fiber sprouting after denervation of the superior colliculus in adult rats. Journal of Neuroscience, 23(18), 7034-7044.
48.
D. Tropea, S. Capsoni, S. Covacheuszak, L. Domenici and A.
Cattaneo, (2002). Rat visual cortical neurons express tyrosin kinase A
(TrkA). Neuroreport, 13(10), 1369-1373.
49. D. Tropea, L. Domenici, (2001).
TrkB expression in visual cortex is not modulated by light. Cell Mol Neurobiol., 21(5), 545-552.
50.
D. Tropea, S. Capsoni, E. Tongiorgi, S. Giannotta, A. Cattaneo and
L. Domenici, (2001). Mismatch between BDNF mRNA and protein
expression in the developing visual cortex. Role of visual experience. Eur. J. Neurosci., 13, 709-721.
51.
D. Tropea, E. Sermasi, L. Domenici, (1999). Long term
potentiation of feedback horizontal connections in rat primary visual cortex. Dev. Brain Res., 118, 61-67.
52.
E. Sermasi, D. Tropea, L. Domenici, (1999). A new form
of synaptic plasticity is transiently expressed in the developing rat visual
cortex: a modulatory role for visual experience and Brain Derived Neurotrophic
Factor. Neuroscience 91(1), 163-173.
53.
E. Sermasi, D. Tropea, L. Domenici, (1999). LTD is
expressed in rat visual cortex: role of visual experience. Brain Res Dev Brain Res 12; 113(1-2), 61-65.