1.     R. Coomey, R. Stowell, A. Majewska, D. Tropea (2020). The Role of Microglia in Neurodevelopmental Disorders and Their Therapeutics. Current Frontiers, In press.

2.     S. Bach, N. M. Ryan, P. Guasoni, A. Corvin, D. Tropea (2019) Methyl-CpG2-binding protein 2 mediates overlapping mechanisms across brain disorders. bioRxiv 819573; doi:

3.      C. Keogh, G. Pini, I. Gemo, D. Tropea. (2019) Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms. J. Vis. Exp. (Pending Publication), e60249, In-press.

4.     A. Sanfeliu, W. Kaufmann, M.Gill, P. Guasoni, D.Tropea (2019). Transcriptomic Studies in Mouse Models of Rett Syndrome: A Review. Forefront Review Neuroscience, 413, 183-205

5.     A. Sanfeliu, K. Hokamp, M. Gill, D. Tropea (2019). Transcriptomic analysis of Mecp2 mutant mice reveals differentially expressed genes and altered mechanisms in both blood and brain. Front Psychiatry. 2019 Apr 29;10:278. doi: 10.3389/fpsyt.2019.00278. eCollection 2019

6.     C. Keogh, G. Pini, A. H. Dyer, S. Bigoni, P. DiMarco, I. Gemo,, R. Reilly, D. Tropea (2018) Clinical and Genetic Rett Syndrome Variants are Defined by Stable Electrophysiological Profiles. BMC Pediatrics, 18(1):333. doi: 10.1186/s12887-018-1304-7

7.     S. Shovlin and D. Tropea (2018). Transcriptome level analysis in Rett syndrome using human samples from different tissues. Orphanet Journal of Rare Diseases, 13(1):113DOI: 10.1186/s13023-018-0857-8.

8.     D. Tropea, N. Hardingham, K. Millar, K. Fox (2018). Mechanisms underlying the role of DISC1 in synaptic plasticity. Invited Review. Journal of Physiology, 596(14): 2747-2771.

9.     D.Tropea, A. Harkin (2017) Biology of brain disorders, editorial. Frontiers in Cellular Neurosciences. 11:366. doi: 10.3389/fncel.2017.00366

10.  A. Ajetunmobi, D, McAllister, Y. Volkov, D.Tropea and A. Prina-Mello. "Characterisation of SH-SY5Y Human Neuroblastoma cell growth over glass and SU-8 substrates."  J Biomed Mater Res A. 2017 Mar 28. doi: 10.1002/jbm.a.36071

11.  S. Wrigley, D. Arafa, D. Tropea (2017). Insulin-Like Growth Factor 1: at the crossroad of neurodevelopment and ageing. Frontiers in Cellular Neuroscience, 11:14. doi: 10.3389/fncel.2017.00014. eCollection 2017.

12.  C.Vadathpour, A.H. Dyer, D.Tropea (2016). Insulin-Like Growth Factor 1 and Related Compounds in the Treatment of Childhood-Onset Neurodevelopmental Disorders. Frontiers in Psychiatry, 10:450. eCollection 2016.

13.  G. Pini G, S. Bigoni, L. Congiu, A.M.Romanelli, M.F. Scusa, P. Di Marco, A. Benincasa, P. Morescalchi, A. Ferlini, F. Bianchi, D. Tropea, M. Zappella (2016). Rett Syndrome: a wide clinical and autonomic picture. Orphanet J Rare Dis. 2016 Sep 29;11(1):132.

14.  D. Tropea, I. Molinos, S. Bellini, M. Gill, A. Corvin (2016). Expression of nuclear Methyl-CpG binding protein 2 (MECP2) is dependent on neuronal stimulation and application of Insulin-like growth factor 1. Neuroscience Letters, 621:111-116.

15.  A.H. Dyer, C.Vadathpuour, A. Sanfeliu, D.Tropea (2016). The role of Insulin-like Growth Factor 1 (IGF1) in brain development, maturation and neuroplasticity. Neuroscience, 325:89-99.

16.  G. Pini, L. Congiu, A. Benincasa, P. Di Marco, S. Bigoni, A. Dyer, N. Mortimer, A. Della Chiesa, S. O'Leary, R. McNamara, K. J. Mitchell, M. Gill and D. Tropea (2016). Illness Severity, Social & Cognitive Ability and EEG Analysis of Ten Patients with Rett Syndrome Treated with Mecasermin (recombinant human IGF-1): A Clinical Study. Autism Research and Treatment.

17.  D.Tropea, I. Molinos, S. Bellini, E. Petit, C. O’Toutaigh, I. Nagakura, K. Mitchell, M. Sur, M. Gill, J. Waddington, A. Corvin (2016). Disrupted in schizophrenia 1 (DISC1) mutants have impaired activity-dependent plasticity in vitro and in vivo. Translational Psychiatry, Jan 12;6:e712. doi: 10.1038/tp.2015.206

18.  Ajetunmobi, A. Prina-Mello, Y.Volkov, A. Corvin, D. Tropea (2014). The era of nanotechnology in the brain: novel approaches to the study of the Central Nervous System. Progress in Neurobiology. 123: 18-36.

19.  D.Tropea, S. Wrigley and G.Pini (2014). Treating Rett Syndrome: current approaches and New Therapies . Book Chapter Rett Syndrome and Other Communication Disorders, ebook, NOVA Science publisher Inc. 2015 New York.

20.  Nagakura, A. Van Wart, J. Petravitz, D. Tropea, M. Sur (2014). STAT1 regulates the homeostatic component of visual cortical plasticity via an AMPA receptor-mediated mechanism. J. Neurosci Jul 30; 34(31):10256-63.

21.  J. Castro, S. Kwok, R. Garcia, A. Banerjee, D. Tropea, M. Sur (2014). Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome. PNAS Jul 8;111(27):9941-6.

22.  G. Pini, M. F. Scusa, A. Benincasa, I. Bottiglioni, L.Congiu, C. Vadhatpour, A. M. Romanelli, I. Gemo, C. Puccetti, R.Mc Namara, S. O’Leary, A. Corvin, M. Gill, D. Tropea (2014). Repeated IGF1 treatment in a patient with Rett Syndrome: a single case study. Frontiers in Pediatrics. Jun 3;2:52. doi: 10.3389/fped.2014.00052. eCollection 2014

23.  Ajetunmobi and D. Tropea. (2014) Progress toward therapies and interventions. Invited book chapter for “The Genetics of Neurodevelopmental Disorders”-Wiley-2015- COS Printer Pte Ltd- Singapore , 319-344.

24.  D.W. Morris, R, Pearson, P. Cormican, e. Kenny, C. O’Dushlaine, LP Lemieux Perreault, e. Gionnoulatou, D. Tropea, et al. (2014). An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis. Hum. Mol. Gen., Jun 15;23(12):3316-26. doi: 10.1093/hmg/ddu025. Epub 2014 Jan 28.

25.  T. O'Donoghue, D.W. Morris, C. Fahey, A. Da Costa, S. Moore, E. Cummings, G. Leicht, S. Karch, D. Hoerold, D. Tropea, J.J. Foxe, M. Gill, A. Corvin, G. Donohoe (2014). Effects of ZNF804A on auditory P300 response in schizophrenia. Transl Psychiatry. 2014 Jan 14;4:e345. doi: 10.1038/tp.2013.115.

26.  E. J. Rose, A. Hargreaves, D. Morris, C. Fahey, D. Tropea, E. Cummings, C. Caltagirone, P. Bossù, C. Chiapponi, F. Piras, G. Spalletta, M. Gill, A. Corvin, G. Donohoe (2013). Effects of a novel schizophrenia risk variant rs7914558 at CNNM2 on brain structure and attributional style. Br J Psychiatry. 2013 Dec 5. [Epub ahead of print]

27.  E.M. Kenny, P. Cormican, S. Furlong, E. Heron, G. Kenny, C. Fahey, E. Kelleher, S. Ennis, D. Tropea, R. Anney, A. P. Corvin, G. Donohoe, L. Gallagher, M. Gill, D. W. Morris, (2013). Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders. Molecular Psychiatry, Oct 15, doi: 10.1038/mp.2013.127.

28.  G. Donohoe, J. Walters, A. Hargreaves, E.J. Rose, D.W. Morris, C. Fahey, S. Bellini, E. Cummins, I. Giegling, A.M. Hartmann, H.J. Moller, P. Muglia, M.J. Owen, M. Gill, M.C. O’Donovan, D. Tropea, D. Rujescu, A. Corvin (2013). Neuropsychological Effects of the CSMD1 Genome-Wide Associated Schizophrenia Risk Variant rs10503253. Genes Brain Behav. 12(2):203-209. Jan 15 Epub..

29.  D. Tropea. New challenges and frontiers in the research for neuropsychiatric disorders (2012). Frontiers in Molecular Psychiatry, 3, 69.

30.  Irish Schizophrenia Genomics Consortium and the Wellcome Trust Case Control Consortium Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia. Biol. Psychiatry 72(8), 620-628.

31.  E. J. Rose, D.W. Morris, C. Fahey, I.H. Robertson, C. Greene, J. O’Doherty, F.N. Newell, H. Garavan, J. Mc Grath, A. Bodke, D. Tropea, M. Gill, AP Corvin, G. Donohoe. The effect of the neurogranin schizophrenia risk variant rs12807809 on brain structure and function. Twin Res. Hum. Genet. 15(3), 296-303.

32.  Corvin, I. Molinos, G. Little G. Donohue, M. Gill, D. Morris, D. Tropea (2012). IGF1 and its active peptide (1-3)IGF1 enhance the expression of synaptic markers in neuronal circuits through different cellular mechanisms. Neuroscience Letters, 520(1), 296-303.

33.  G. Pini, M.F. Scusa, B. Felloni, L. Congiu, A. Benincasa, R. Frati, I. Bottiglioni, P. Di Marco, P. Borelli, U. Bonuccelli, A. Della-Chiesa, A. Prina-Mello, D. Tropea (2012). Safety assessment of IGF-1 treatment: study on six Rett patients. Autism research and treatment, 2012:679801, Epub Jun 13.

34.  Hargreaves, D.W. Morris, E. Rose, C. Fahey, S. Moore, E. Cummings, D. Tropea, M. Gill, A. Corvin, G. Donohoe (2012). ZNF804A and social cognition in patients with schizophrenia and healthy controls. Mol Psychiatry., Feb;17(2), 118-119.

35.  Delaney, J. McGrane, E. Cummings, DW Morris, D. Tropea, M. Gill, A. Corvin, G. Donohoe. Preserved Cognitive function is associated with suicidal ideation and single suicide attempts in schizophrenia. Schizophr. Res. 140 (1-3), 232-236.

36.  T. O’Donohoe, D.W. Morris, C. Fahey, A. Da Costa, J.J. Foxe, D. Hoerold, D. Tropea, m. Gill, A. Corvin, G. Donohoe (2012). A NOS1 variant implicated in cognitive performance influences evoked neural responses during a high density EEG study of early visual perception. Hum. Brain Mapp, 33(5), 1202-1211.

37.  N. Mellios, H. Sugihara, J. Castro, A. Banerjee, C. Le, A. Kumar, B. Crawford, J. Strathmann, D. Tropea, S. S. Levine, D. Edbauer, M. Sur (2011). miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity. Nature Neurosci.,40, 1240-1242.

38.  D. Tropea, M. Sur,A. Majewska (2010) Experience-dependent plasticity in visual cortex: dendritic spines and visual responsiveness. Communicative and Integrative Biology 4(2), 216-219.

39.  D. Tropea, A. Majewska, R. Garcia, M. Sur (2010) Structural dynamics of synapses in vivo correlate with functional changes during experience-dependent plasticity in visual cortex. Journal of Neurosci. 30(33), 11086-11095.

40.  C.L. McCurry, J.D. Shepherd, D. Tropea, KH Wang, M.F. Bear, M. Sur (2010) Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation. Nat. Neurosci. Apr;13(4), 450-457

41.  D. Tropea, E. Giacometti, N. Wilson, Caroline Beard, Cortina McCurry, Dong Dong Fu, Ruth Flannery, R. Jaenisch and M. Sur (2009) Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice. PNAS, 106 (6), 2029-2034.

42.  M. Caleo, D. Tropea, C. Rossi, L. Gianfranceschi and L. Maffei (2009) Environmental enrichment promotes fiber sprouting after deafferentation of the superior colliculus in the adult rat brain. Exp. Neurol., Apr 216 (2), 515-519.

43.  D. Tropea, A. Van Wart and M Sur (2008). Review. Molecular mechanisms of experience-dependent plasticity in visual cortex. Philos .Trans. R. Soc. Lond B Biol Sci. 364 (1515), 341-355.

44.  Lyckman, S. Horng, C. Leamey, D. Tropea, A. Watakabe, A. Van Wart, C. McCurry, T. Yamamori and M. Sur (2008). Transcriptional regulation during the critical period of ocular dominance plasticity: prominent expression of actin-binding and myelination factors. PNAS, 105 (27), 9409-9414.

45.  D. Tropea, G. Kreiman, A. Lyckman, S. Mukherjee, H. Yu, S. Horng and M. Sur (2006). Gene expression changes and molecular pathways mediating activity-dependent plasticity in visual cortex. Nature Neuroscience, 9(5), 660-668.

46.  P.P Pattabiraman, D. Tropea, C. Chiaruttini, E. Tongiorgi, A. Cattaneo and L. Domenici (2005). Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo. Mol. Cell. Neurosci. 28(3), 556-570.

47.  D. Tropea, M. Caleo and L. Maffei, (2003). Synergistic effects of brain-derived neurotrophic factor and chondroitinase ABC on retinal fiber sprouting after denervation of the superior colliculus in adult rats. Journal of Neuroscience, 23(18), 7034-7044.

48.  D. Tropea, S. Capsoni, S. Covacheuszak, L. Domenici and A. Cattaneo, (2002). Rat visual cortical neurons express tyrosin kinase A (TrkA). Neuroreport, 13(10), 1369-1373.

49.  D. Tropea, L. Domenici, (2001). TrkB expression in visual cortex is not modulated by light. Cell Mol Neurobiol., 21(5), 545-552.

50.  D. Tropea, S. Capsoni, E. Tongiorgi, S. Giannotta, A. Cattaneo and L. Domenici, (2001). Mismatch between BDNF mRNA and protein expression in the developing visual cortex. Role of visual experience. Eur. J. Neurosci., 13, 709-721.

51.  D. Tropea, E. Sermasi, L. Domenici, (1999). Long term potentiation of feedback horizontal connections in rat primary visual cortex. Dev. Brain Res., 118, 61-67.

52.  E. Sermasi, D. Tropea, L. Domenici, (1999). A new form of synaptic plasticity is transiently expressed in the developing rat visual cortex: a modulatory role for visual experience and Brain Derived Neurotrophic Factor. Neuroscience 91(1), 163-173.

53.  E. Sermasi, D. Tropea, L. Domenici, (1999). LTD is expressed in rat visual cortex: role of visual experience. Brain Res Dev Brain Res 12; 113(1-2), 61-65.

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